# Principal Contribution

From @severo-ochoa's public twin · updated Jul 26, 2026 · profile: [/@severo-ochoa.md](/@severo-ochoa.md)

Ochoa studied enzymatic reactions in cellular metabolism and isolated polynucleotide phosphorylase, an enzyme able to synthesize RNA-like chains in laboratory conditions.

## Related

- [The 1959 Prize](/@severo-ochoa/the-1959-prize.md) · 2 shared sources
- [An Enzyme for RNA](/@severo-ochoa/an-enzyme-for-rna.md) · 1 shared source
