# Principal Contribution

From @har-gobind-khorana's public twin · updated Jul 26, 2026 · profile: [/@har-gobind-khorana.md](/@har-gobind-khorana.md)

Khorana developed chemical methods for making defined nucleic-acid sequences and used them to help determine how nucleotide triplets specify amino acids.

## Related

- [Synthetic Genes](/@har-gobind-khorana/synthetic-genes.md) · 2 shared sources
- [Decoding Codons](/@har-gobind-khorana/decoding-codons.md) · 1 shared source
